Page 56 - Htain Manual

o Equity and socio-cultural review – literature on equity-related and other social

issues around the interventions in question

o Gaps in literature – existing gaps/lacunae in the literature that your study
would fill in; usually the lack of local/Indian evidence

 Aim of the Study

 Objectives of the Study

o Primary objectives

o Secondary objectives

 PICOT (Population, Intervention, Comparator, Outcome, Timeline)

o Additional specifics like costing perspective, time horizon for analysis and cycle

length to be specified where relevant.

 Methodology

o Conceptual Framework and Model Overview (Decision tree or Markov;
whichever is to used)

o Estimation of Costs – How and what costs would be considered and analysed

o Health Outcome Valuations – What health outcomes are being taken in terms

of the cost effectiveness analysis

o Discounting – The discounting rate chosen with its justification

o Sensitivity Analysis (which one will be done and its method)

 Ethical Justification/Considerations – if required

 References – Any and all papers used for reference in Vancouver style

 Annexures – Any data collection tool that would be used in the study

This completes all the requisites of how a proposal should be framed. A complete proposal is

the key to undertaking a full-fledged and meaningful HTA.

44